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Year : 2013  |  Volume : 3  |  Issue : 2  |  Page : 159-160

Polyuria following an overdose

Intensive Care Unit, Royal Bournemouth Hospital, Castle Lane East, Bournemouth, Dorset BH7 7DW, United Kingdom

Correspondence Address:
Angela Collins
James Paget University Hospital, Lowestoft Road, Gorleston, Great Yarmouth, Norfolk NR31 6LA
United Kingdom
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5151.114277

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Case report detailing the occurrence of diabetes insipidus in a 42-year-old man admitted to the intensive treatment unit (ITU) following an overdose. Whilst on ITU, he was sedated with propofol. Cessation of treatment with propofol coincided with resolution of the polyuria. Animal studies suggest a theoretical mechanism for propofol as the causative agent, but this phenomenon is not commonly seen in humans.

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